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S100B is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs and has been implicated in the regulation of cellular activities such as metabolism, motility and proliferation. In the nervous system, S100B is constitutively released by astrocytes into the extracellular space and at nanomolar concentrations. Serum levels of S100B increase in patients during the acute phase of brain damage. Over the last decade, S100B has emerged as a candidate peripheral biomarker of blood–brain barrier (BBB) permeability and CNS injury. Elevated S100B levels accurately reflect the presence of neuropathological conditions including traumatic head injury or neurodegenerative diseases.

Catalog Number: 

Attribute: Rabbit Polyclonal Antibody

Isotype: IgG

Purity: Antigen Affinity Purification

Application: ELISA, WB, IP

Calculated MW: 10kDa

Observed MW: 10kda,20kDa(dimer)

Reactivity: Human,Mouse,Rat,Zebra fish

Immunogen: Recombinant Human S100B protein expressed by E.Coli   

Buffer: PBS with 0.1% sodium azide and 50% glycerol, pH 7.2

Storage: Store at -20℃. Do not aliquot

Recommended Dilution:

WB: 1:1000-2000

IP: 1:5000-10000

IF: 1:100-200