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商品編號


JP10411



品牌


IBL



公司


IBL,inc



公司分類


Antibodies


商品信息

Quantity / Tests
100 ?g
Species / Antigen
human
Host
mouse
Subclass / Clone
ADPYDMAB
Type
Monoclonal
Purification
Affinity Purification with protein A
Label
No
Regulatory Status:
For research use only


Details for:


?
Anti-DPD (ADPYDMAB) Mouse IgG

Thymidylate synthase (TS; EC 2.1.1.45), Dihydropyrimidine dehydrogenase (DPD; EC 1.3.1.2), Thymidene phosphorylase (TP; EC 2.4.2.4) and Orate phosphorybosyl transferase (OPRT; EC 2.4.2.10) are known as key enzymes related to nucleic-acid metabolism within the body.
These enzymes are also known to be related to activation, metabolism and catabolism of 5-FU (5-fluorouracil) which is a metabolic antago
NIST
being widely used for treatment of solid cancers including cancers of the digestive system and breast cancer. Some publications show a correlation between these enzymes and the effects of 5-FU-based anticancer drugs.
Additionally, TS and DPD have been reported to be prognosticating factors for individuals who suffer from these different cancers.
This antibody is useful for research of nucleic acid and expression of those proteins in cancer tissues.

Distributed by
IBL
International

For concrete data please consult the Instruction for Use in the download box on the right side.