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商品編號(hào)


30112278



品牌


IBL



公司


IBL,inc



公司分類


Antibodies


商品信息

Quantity / Tests
50 ?g
Species / Antigen
Synthetic peptide (RKTEDT(pY)FISSAG)
Host
Rabbit
Subclass / Clone
IgG
Type
Polyclonal
Purification
Affinity Purification
Label
No
Regulatory Status:
For research use only


Details for:


?
Anti-human Girdin (Phosph-Y1764) Rabbit IgG

"Original article #28145
Girdin is a new protein playing an important role in the infiltration and metastasis of cancer cells. A new substance of protein kinase B, Girdin (Girders of actin filament) was discovered by a research group led by Takahashi et al., Nagoya University by screening using yeast two-hybrid method and was elucidated that Girdin has an important role for cell migration downstream of protein kinase B.

It has been proven that Girdin is a new actin binding protein and it restructures actin fibers upon phosphorylation by protein kinase B and it is involved in formation of lamellipodia that are located at the le
ADI
ng edge of cells and play an important role for cell migration by functional analysis. Various antibodies inclusive phosphorylated Girdin antibodies are provided by
IBL
and it has been suggested that the change of condition of phosphorylated Girdin is involved in structure alteration in relation to cell migration in vivo or in vitro by current studies used these antibodies."

For concrete data please consult the Instruction for Use in the download box on the right side.